National Institutes of Health Grants

Open National Institutes of Health grants

• Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)

  Up to $8.0MDeadline: Jan 25, 2028open

  This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting facilities that enabl...

• Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)

  Up to $6.3MDeadline: Nov 15, 2027open

  The purpose of this Notice of Funding Opportunity (NOFO) is to leverage NICHD clinical research Network infrastructure relevant to infants, children, ...

• Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

  Up to $5.0MDeadline: Jul 1, 2028open

  This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing share...

• Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  Up to $3.0MDeadline: Aug 21, 2028open

  The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions ...

• GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

  Up to $2.3MDeadline: Oct 30, 2026open

  The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease ...

• Single Source for Continuation of the Integrated Islet Distribution Program U24 (Clinical Trial Not Allowed)

  Up to $2.2MDeadline: Sep 30, 2026open

  This is a NOFO for a Single Source competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section ...

• Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training (U2C - Clinical Trial Not Allowed)

  Up to $2.1MDeadline: May 26, 2028open

  Responding to the needs of the scientific community to bolster a vibrant and sustainable research workforce, the Division of Kidney, Urologic, and Hem...

• Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)

  Up to $2.0MDeadline: Oct 2, 2026open

  Max award: $2,000,000 Eligibility: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organi...

• Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)

  Up to $2.0MDeadline: Oct 2, 2026open

  The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Inte...

• Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)

  Up to $1.8MDeadline: Sep 25, 2028open

  The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Train...

• NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

  Up to $1.5MDeadline: Jan 7, 2027open

  The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions f...

• Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center (U24 Clinical Trial Not Allowed)

  Up to $1.5MDeadline: Sep 29, 2026open

  Max award: $1,500,000 Eligibility: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organi...

• Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center (U24 Clinical Trial Not Allowed)

  Up to $1.5MDeadline: Sep 29, 2026open

  The purpose of this Notice of Funding Opportunity (NOFO) is to support the next 5-year award period of the Clinician-Scientist Transdisciplinary Aging...

• Single Source Competition: Continuation of the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) - Resource Center (U24 Clinical Trial Not Allowed)

  Up to $1.5MDeadline: Sep 30, 2026open

  This Notice of Funding Opportunity (NOFO) invites a single cooperative agreement application for the Resource Center for the Cardiovascular Repository...

• Single Source Competition: Continuation of the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) - Resource Center (U24 Clinical Trial Not Allowed)

  Up to $1.5MDeadline: Sep 30, 2026open

  Max award: $1,500,000 Eligibility: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Only the foll...

• High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)

  Up to $1.5MDeadline: Mar 5, 2027open

  The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA...

• Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

  Up to $1.5MDeadline: Nov 5, 2027open

  The goal of this Notice of Funding Opportunity (NOFO) is to provide funding support for the pre-clinical and early stage clinical (Phase I) developmen...

• Metastasis Research Network (U54 Clinical Trial Not Allowed)

  Up to $1.3MDeadline: Sep 25, 2026open

  Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on developing a comprehensiv...

• GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

  Up to $1.3MDeadline: Oct 30, 2026open

  The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease ...

• NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

  Up to $1.1MDeadline: Nov 13, 2026open

  This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., ...

Where National Institutes of Health grants go

Recent grant recipients are concentrated in these states. Funders sometimes fund outside their primary states for high-fit projects, so don't self-eliminate solely on geography — check each opportunity's stated eligibility.

What National Institutes of Health funds

Top program areas based on GrantMind's analysis of recent National Institutes of Health awards:

How to apply for National Institutes of Health grants

Most National Institutes of Health applications require: an organizational profile with mission and programs, a project proposal aligned with the funder's stated priorities, a project budget, and supporting attachments (IRS determination letter, board list, recent financials). Federal applicants additionally need a SAM.gov UEI and an active Grants.gov account.