National Cancer Institute Grants

Open National Cancer Institute grants

• Convergent Epigenetic Control of Neuroendocrine Cancers

  Up to $2.4MDeadline: Mar 31, 2030open

  Summary (Overall) The overall goal of the Program “Convergent Epigenetic Control of Diverse Neuroendocrine Cancers” is to interrogate epigenetic and ...

• Algorithm-enabled Patients Activated in Cancer care through Teams (A-PACT) toimprove goals of care communication for people with cancer

  Up to $708KDeadline: Feb 28, 2030open

  /Abstract For patients with cancer, goals of care (GoC) conversations regarding prognosis, values, and advance care planning are a critical but greatl...

• A systems-level approach to therapeutically target STING in cancer

  Up to $702KDeadline: Feb 28, 2030open

  Most proteins have more than one function and participate in a wide range of biological processes. This compli- cates our ability to infer protein fun...

• Electronic health record (EHR)-based implementation strategies and decision support for hereditary breast and ovarian cancer (HBOC) genetic testing among multiethnic women (ELISABETH)

  Up to $687KDeadline: Feb 28, 2027open

  About 5-10% of breast cancers and 10-15% of ovarian cancers are attributed to pathogenic variants (PVs) in cancer predisposition genes, such as BRCA1 ...

• Dissecting the hematopoietic pathways governing age-associated pathogenic myelopoiesis

  Up to $680KDeadline: Feb 28, 2030open

  Chronic inflammation is a key factor contributing to age-related risks of tumor occurrence and progression. Myeloid cells of the immune system, such a...

• Role of respiratory viral infections and inflammation in promoting metastatic outgrowth in the lung

  Up to $658KDeadline: Feb 28, 2030open

  The leading cause of breast cancer deaths is metastasis. Metastatic relapse can occur months to years after the initial diagnosis and treatment of the...

• Improving Management of patients at High Risk of Pancreatic Cancer

  Up to $654KDeadline: Jan 31, 2030open

  Our overall goal is to redefine screening for early detection of pancreatic cancer. Currently, endoscopic ultrasound and magnetic resonance imaging (M...

• Self-sampling to Optimize Anal Lesion Outcomes (SOLO)

  Up to $652KDeadline: Feb 28, 2030open

  Human papillomavirus causes squamous cell carcinoma of the anus (SCCA) which has a heterogenous incidence depending on population; thus, this applicat...

• Deciphering the role of EYA3/PP2A in triple negative breast cancer metastasis

  Up to $647KDeadline: Feb 28, 2030open

  Breast cancer (BC) is one of the most diagnosed cancers in women (second only to skin cancer) and comprises ~30% of all new female cancers each year. ...

• Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors

  Up to $627KDeadline: Jan 31, 2030open

  The goal of this proposal is to optimize the efficacy of CAR T cells against pancreatic tumors using engineered, synthetic cytokine receptors (velocit...

• Targeting chromatin acetylation factors in multiple myeloma

  Up to $623KDeadline: Feb 28, 2030open

  Multiple myeloma is a disease characterized by aberrant chromatin accessibility and gene expression. Principle mediators of this dysregulation are chr...

• Deregulation of Sulfatide Synthesis in the Development and Progression of Pancreatic Cancer Precursor Lesions

  Up to $616KDeadline: Feb 28, 2030open

  The existence of asymptomatic precursor lesions that are known to predate invasive pancreatic ductal adenocarcinoma (PDAC) by years provides a compell...

• Innovative Scan Protocols With Combined Long Axial FOV PET and Spectral CT for Improved Quantification in Oncology

  Up to $600KDeadline: Dec 31, 2028open

  Innovative scan protocols with combined long axial FOV PET and spectral CT for improved quantification in oncology: The goal of this project is to i) ...

• PD-L1 MODIFICATIONS IN CANCER DIAGNOSIS AND TREATMENT

  Up to $597KDeadline: Jan 31, 2030open

  PD-L1 Modifications in Cancer Diagnosis and Treatment PROJECT SUMMARY Programmed death ligand 1 (PD-L1, also known as CD274 or B7-H1) is the principal...

• A novel therapeutic strategy to target mutant p53

  Up to $591KDeadline: Feb 28, 2030open

  /Abstract Mutation of the tumor suppressor gene TP53 occurs in more than half of human cancers. Mutant p53 is known to actively drives tumor progressi...

• Developing purinergic receptor inverse agonists for treating triple negative breast cancer

  Up to $568KDeadline: Jan 31, 2030open

  Summary We propose to develop novel adenosine receptor inverse agonists for the treatment of metastatic triple negative breast cancer (TNBC). An estim...

• Novel functions of PlexinB2 in circulating tumor cell clusters

  Up to $546KDeadline: Jan 31, 2030open

  The outcomes of cancer metastasis result from the dynamic battles and interactive reprogramming between malignant cancer cells and the host defense sy...

• Mechanisms of Papillomavirus Tumor Regression by MEK Signaling Inhibition

  Up to $545KDeadline: Feb 28, 2030open

  Human papillomaviruses (HPVs) are highly transmissible causative agents of benign and malignant tumors/ neoplasia in squamous epithelium. Despite prop...

• Impact of State Cannabis Laws on Cancer Pain Management and Outcomes: A mixed-methods study

  Up to $528KDeadline: Jul 31, 2029open

  /ABSTRACT More than one third of the approximately 2 million Americans diagnosed with cancer each year experience moderate to severe pain related to t...

• Targeting APOBEC3-induced squamous differentiation in bladder cancer

  Up to $515KDeadline: Feb 28, 2030open

  In 2023, there will be an estimated 81,180 new cases of bladder cancer in the United States, resulting in an estimated 17,100 deaths. Over 90% of blad...

Where National Cancer Institute grants go

Recent grant recipients are concentrated in these states. Funders sometimes fund outside their primary states for high-fit projects, so don't self-eliminate solely on geography — check each opportunity's stated eligibility.

What National Cancer Institute funds

Top program areas based on GrantMind's analysis of recent National Cancer Institute awards:

How to apply for National Cancer Institute grants

Most National Cancer Institute applications require: an organizational profile with mission and programs, a project proposal aligned with the funder's stated priorities, a project budget, and supporting attachments (IRS determination letter, board list, recent financials). Federal applicants additionally need a SAM.gov UEI and an active Grants.gov account.