National Cancer Institute Grants

Open National Cancer Institute grants

• Strategically Engineered Multi-Antigen KSHV Vaccine: Integrating Humoral and Cellular Immunity for Effective Protection

  Up to $4.9MDeadline: Jul 31, 2029open

  /Abstract Infection of Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8 (HHV-8), is estimated to account for 34,000 ne...

• Conversational Agent to Improve Guideline Concordant Care for People with Cervical Cancer Screening Abnormalities

  Up to $3.3MDeadline: Jul 31, 2029open

  / ABSTRACT Cervical cancer is almost entirely preventable with appropriate screening and management of abnormal results, yet in the US, over 14,000 in...

• Magnetic Resonance Fingerprinting of Glutamate Metabolism for Guiding Glioma Cancer Care

  Up to $3.2MDeadline: Jul 31, 2029open

  Glioblastoma (GBM) is the most common type of malignant primary brain tumor found in adults and is fatal in all cases with a median survival time of o...

• Controllable solid tumor immunotherapy based on a wireless thermos-activator

  Up to $3.0MDeadline: Jul 31, 2029open

  Chimeric Antigen Receptor (CAR) T cell therapy is a groundbreaking treatment for cancer, with the potential to elicit long-lasting immune responses. H...

• Non-invasive etiology-adjusted precision liver cancer risk prediction

  Up to $2.9MDeadline: Jul 31, 2029open

  Hepatocellular carcinoma (HCC) is the major histological type of liver cancer, caused by viral (HBV, HCV) and metabolic (alcohol, metabolic dysfunctio...

• Impact of CAR and Nrf2 dual activation on cyclophosphamide bioactivation and doxorubicin detoxification

  Up to $2.8MDeadline: Jul 30, 2029open

  Cyclophosphamide (CPA) and doxorubicin (DOX)-containing regimens are extensively utilized in treating various malignancies, including triple-negative ...

• Supporting Informed Parental Decisions on HPV Vaccination through Safe and Personalized AI-Driven Conversations

  Up to $2.8MDeadline: Jul 31, 2029open

  This project aims to support informed decision making about Human Papillomavirus (HPV) vaccination among parents of adolescents in the United States t...

• New methods to measure and interrupt metabolic fluxes in brain cancer

  Up to $2.8MDeadline: Jul 31, 2029open

  Glioblastomas (GBMs) are deadly incurable brain cancers that are treated with resection followed by radiation, which is often combined with chemothera...

• Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging

  Up to $2.7MDeadline: Jul 31, 2030open

  Paclitaxel-induced peripheral neuropathy (PIPN) is a common painful treatment side effect that affects millions of cancer patients. Currently there ar...

• Nanotechnology enabled quantitative imaging of dendritic cell anti-cancer vaccines

  Up to $2.6MDeadline: Jul 31, 2029open

  Dendritic cells (DCs) are pivotal in mediating anti-tumor immunity, and an effective DC vaccine devoid of intolerable immune-related toxicity would be...

• Fluorescence guided nerve sparing during colorectal cancer surgery using local application of a near infrared nerve fluorophore

  Up to $2.5MDeadline: Jul 31, 2029open

  Colorectal cancer (CRC) is the second leading cause of cancer death and is predicted to cause nearly 10% of cancer deaths worldwide in 2024. Rectal ca...

• CP-CTNet Coordinating Center

  Up to $2.5MDeadline: Jul 31, 2031open

  /Abstract Cancer is the leading cause of morbidity and mortality in the US and in the world. One approach to reducing the risk and burden of cancer is...

• Targeting Myeloid Metabolism to Reprogram the Tumor Microenvironment of Glioblastoma

  Up to $2.5MDeadline: Jul 31, 2029open

  IDH1R132H mutation is recognized as the most common initiating event for low-grade glioma and IDH1- mutant grade IV astrocytoma. Our recent study (Ste...

• ROLE OF RNA SEQUESTRATION IN ACUTE MYELOID LEUKEMIA

  Up to $2.4MDeadline: Jul 31, 2029open

  Post-transcriptional mechanisms play crucial roles in maintenance of progenitor cell identity and have been implicated in cancer development, includin...

• Convergent Epigenetic Control of Neuroendocrine Cancers

  Up to $2.4MDeadline: Mar 31, 2030open

  Summary (Overall) The overall goal of the Program “Convergent Epigenetic Control of Diverse Neuroendocrine Cancers” is to interrogate epigenetic and ...

• The impact of dyadic processes on smoking and cigarette craving: An experimental investigation of romantic partners and smoking friends

  Up to $2.2MDeadline: Jul 31, 2029open

  Smoking is the leading preventable cause of cancer and mortality in the US, with Covid hitting smokers especially hard. Quitting is difficult (and smo...

• FY25 TASK ORDER D - BASE: WO 126680 B539 EAST BASEMENT SWITCHBOARDREPLACEMENT. OPTION 1: 126680A B539 WEST ATTIC SWITCHBOARDREPLACEMENT

  Up to $2.0MDeadline: Mar 3, 2028open

  Base - The purpose of this project is to replace five aged switchboards in the East Basement of B539 with new code compliant switchboards. Additional ...

• Principles of Speckle-Based Gene Regulation

  Up to $1.7MDeadline: Jul 31, 2028open

  The cell nucleus houses different types of non-DNA substructures, called nuclear bodies. Among these, nuclear speckles predominate. Speckles occupy ~1...

• Deep Learning Serial Radiomics for Improved Cancer Therapy Response Assessment.

  Up to $1.7MDeadline: Jul 31, 2027open

  Summary This Direct to Phase II SBIR proposal aims to further develop and validate a deep learning radiomics biomarker for improved early response ass...

• A Phase 1-2 clinical program for the teatment of Microsatellite Stable Colorectal Cancer with the combination of SR-8541A, Botensilimab, and Balstilimab

  Up to $1.5MDeadline: Jul 31, 2028open

  Metastatic microsatellite stable colorectal cancer (MSS-CRC) accounts for 80% of CRCs with a standard of care that provides a dismal 10% objective res...

Where National Cancer Institute grants go

Recent grant recipients are concentrated in these states. Funders sometimes fund outside their primary states for high-fit projects, so don't self-eliminate solely on geography — check each opportunity's stated eligibility.

What National Cancer Institute funds

Top program areas based on GrantMind's analysis of recent National Cancer Institute awards:

How to apply for National Cancer Institute grants

Most National Cancer Institute applications require: an organizational profile with mission and programs, a project proposal aligned with the funder's stated priorities, a project budget, and supporting attachments (IRS determination letter, board list, recent financials). Federal applicants additionally need a SAM.gov UEI and an active Grants.gov account.