National Institute of Dental and Craniofacial Research Grants

Open National Institute of Dental and Craniofacial Research grants

• Targeting Succinate Signaling for Innovative Pain Relief in Oral Cancer.

  Up to $3.9MDeadline: Aug 31, 2029open

  Current pain management strategies for patients with oral or head and neck cancer conditions often rely on high-dose opioid analgesics, which can be i...

• Dissecting CCL5 contribution to antigen specific T cell responses in head and neck cancers

  Up to $3.7MDeadline: Aug 20, 2029open

  Correlative studies of immune checkpoint blockade (ICB) show that response is highly dependent on the quantitative and qualitative status of pre-exist...

• Collaborative for REsearch to AdvanceTMD Evidence (CREATE)

  Up to $3.5MDeadline: Jun 30, 2030open

  Temporomandibular disorders (TMDs) involve complex and poorly understood pathophysiological processes, limiting prevention, diagnosis, prognosis and t...

• 360° Collaborative Hub for AI in TMD Research (360° Chat-TMD)

  Up to $3.0MDeadline: Jun 30, 2030open

  360° CHAT TMD ABSTRACT The proposed 360° Collaborative Hub for AI in TMD Research (360° CHAT-TMD) Center will establish a national, interdisciplinary,...

• Analysis of high dimensional genomic dataset to reveal mechanistic insights on divergent outcomes of head and neck cancer using system biology modeling coupled with experimental validation

  Up to $1.9MDeadline: Sep 18, 2028open

  /Abstract In response to PAR-23-133, we propose to use high-dimensional datasets of human head and neck squamous cell carcinomas (HNSCC) available in...

• Advancing Craniosynostosis Treatment (ACT)Rare Diseases Consortium

  Up to $1.5MDeadline: May 31, 2030open

  OVERALL The overall goal of the Advancing Craniosynostosis (ACT) Rare Diseases Consortium is to advance diagnosis, management, and treatment of the 5 ...

• Point of Care Detection of HPV and P16 in Saliva

  Up to $1.4MDeadline: Jul 31, 2027open

  Oropharyngeal squamous cell carcinoma (OPSCC) is the sixth most common cancer globally, with its incidence rising due to high-risk HPV infections, par...

• Leveraging Advances in Practices and Outcomes in Cleft Care: The LEAP Study

  Up to $1.3MDeadline: Jun 30, 2030open

  Currently, there are limited coordinated efforts to rapidly improve care for children born with cleft lip and/or palate directly at the site where car...

• A Team Science Approach to the Co Development of Oral Mucosa for Therapeutic Purposes

  Up to $1.2MDeadline: May 31, 2030open

  The oral cavity soft tissues protect against pathogens, toxins, and trauma. Over 100,000 soft tissue grafts are performed annually in the U.S. after t...

• AI-linked cytomics-on-a-chip to enable near-real time identification and management of oral lichenoid lesions in primary care

  Up to $1.2MDeadline: Mar 31, 2027open

  Oral cancer, which affects 54,000 Americans per year, has one of the worst outcomes and highest expense rates of all cancers, in large part due to lat...

• Regeneration of radiation-damaged salivary glands using neurogenicstimulation of stem cells

  Up to $1.0MDeadline: Jun 30, 2027open

  Xerostomia (dry mouth) is a disease caused by reduced or lost salivary gland function that leads to a significantly diminished quality of life and poo...

• Commercialization Readiness Pilot for A Comprehensive Platform for Pediatric Cranial Evaluation

  Up to $1.0MDeadline: Aug 11, 2027open

  Delayed identification of infant head conditions is causing unnecessary medical complications and societal costs. A critical challenge in early detect...

• Enhancing Dental and Craniomaxillofacial Surgery Outcomes with Cost-Effective and Scalable Animal-Free Amino Acid-Based Membranes for Guided Bone Regeneration

  Up to $976KDeadline: Jun 30, 2027open

  Regenerative strategies for oral and craniomaxillofacial (CMF) defects using autogenous bone grafts are often constrained by limited availability and ...

• Broader Evaluation of TMD Treatment Efficacy and Response (BETTER TMD)

  Up to $897KDeadline: Jun 30, 2030open

  / ABSTRACT (Project 1 BETTER TMD) C-TMD IMPACT Research Project 1 refers to Broader Evaluation of TMD Treatment Efficacy & Response (BETTER-TMD) and w...

• Bioinformatics/data science Core (BDSC)

  Up to $869KDeadline: Jun 30, 2030open

  The Bioinformatics and Data Science Core (BDSC) aims to advance the study of temporomandibular disorders (TMDs) through a modern data-driven framework...

• Single-Cell-Resolved Mapping and Evolution-Driven Functional Interrogation of Human Midface Enhancers

  Up to $804KDeadline: Mar 31, 2030open

  SUMMARY Developmental anomalies of the midface, including clefts of the lip and palate, are a common feature of congenital disorders. They can substan...

• Developmental Systems Genomics of morphogenetic timing and facial shape variation

  Up to $796KDeadline: Feb 28, 2031open

  The objective of this proposal is to elucidate the complex genetic, transcriptional, and histological landscape underpinning palate morphogenesis by l...

• Mechanisms of Macroglossia in Beckwith-Wiedemann Syndrome

  Up to $781KDeadline: Jan 31, 2030open

  /ABSTRACT Macroglossia (severe tongue overgrowth) leads to catastrophic morbidity and mortality in infants with Beckwith-Wiedemann Syndrome (BWS). Res...

• Genetic Regulatory Network in Craniofacial Development

  Up to $762KDeadline: Jan 31, 2030open

  This competitive renewal continues our efforts to decipher the skeletogenic signaling network underlying craniofacial development and disease. The cra...

• Cartilage and bone of the lower jaw in development and disease

  Up to $761KDeadline: Jan 31, 2027open

  The lower jaw evolved as a structure composed of many bones the largest of which, the dentary, persists as a single lower jawbone in modern mammals, a...

Where National Institute of Dental and Craniofacial Research grants go

Recent grant recipients are concentrated in these states. Funders sometimes fund outside their primary states for high-fit projects, so don't self-eliminate solely on geography — check each opportunity's stated eligibility.

How to apply for National Institute of Dental and Craniofacial Research grants

Most National Institute of Dental and Craniofacial Research applications require: an organizational profile with mission and programs, a project proposal aligned with the funder's stated priorities, a project budget, and supporting attachments (IRS determination letter, board list, recent financials). Federal applicants additionally need a SAM.gov UEI and an active Grants.gov account.