National Institute of Mental Health Grants

Open National Institute of Mental Health grants

• Cross Scale Interrogation of NPD Genes (SING) in mice

  Up to $3.8MDeadline: Nov 30, 2029open

  Neurodevelopmental and psychiatric disorders (NPDs) are highly prevalent and devasting neurological conditions without cure. Recent genetic studies on...

• Dissecting the circuits and population dynamics that represent unconditioned and conditioned stimuli in the ventral hippocampus

  Up to $781KDeadline: Dec 31, 2029open

  Neural population dynamics are in constant flux, with patterns of activity across neurons being updated to account for changes in the relationships be...

• Non-synaptic function of Syngap1 in human neurodevelopmental disorders

  Up to $773KDeadline: Dec 31, 2029open

  SUMMARY Advances in human genomics have dramatically accelerated our understanding of the genetics of complex brain disorders, including autism spect...

• Precision TMS with integrated visualization and analysis of real-time E-field and EEG source imaging

  Up to $752KDeadline: Jan 31, 2030open

  Summary Transcranial magnetic stimulation (TMS) is an FDA-approved treatment for several brain diseases, such as major depressive disorder, obsessive-...

• Evaluating Social Brain Health in HIV: An RDoC-based approach

  Up to $733KDeadline: Jan 31, 2030open

  Evaluating Social Brain Health in HIV: An RDoC-based Approach In our daily life, we frequently interact with others (e.g., friends, staff at grocery s...

• Neuroimaging Studies of Reward Processing in Depression

  Up to $603KDeadline: Feb 28, 2027open

  Major Depressive Disorder (MDD) remains a major public health problem with poorly understood etiology and pathophysiology. Impairment in reward proce...

• Brain Network Mechanisms of Rapid Instructed Task Learning

  Up to $565KDeadline: Feb 23, 2027open

  /ABSTRACT The ability to quickly learn novel cognitive procedures from instructions – rapid instructed task learning (RITL; “rittle”) – is substantial...

• Harnessing Data Science to Improve HIV Care Continuum Outcomes: A Hybrid Type 2 Trial Evaluating a Machine-Learning Algorithm-Based Implementation Strategy

  Up to $554KDeadline: Jan 31, 2030open

  7. PROJECT SUMMARY Innovations in treatment and care for people with HIV (PWH) have had tremendous positive impacts on health, longevity and quality o...

• Advanced culture and recording system for long-term electrophysiological profiling in human brain organoids

  Up to $449KDeadline: Feb 28, 2027open

  Summary/Abstract Brain organoids, derived from human pluripotent stem cells, represent a groundbreaking model system for basic and applied neuroscienc...

• Identifying the neural correlates of mental simulation in multi-step planning

  Up to $390KDeadline: Jan 31, 2030open

  /ABSTRACT Planning, the ability to mentally simulate possible futures toward a goal, is essential for everyday decision-making. Indeed, many psychiatr...

• The Caregiver-Informed Treatment Engagement (CITE) Program: a Pilot Trial of a Treatment Engagement Intervention for Historically Underserved Youth

  Up to $243KDeadline: Nov 30, 2027open

  . Mental illness is common, impairing, and associated with heightened suicide risk among youth, but access to proper care is sorely limited, particula...

• Intracranial Recording and Stimulation of the Human Hippocampal-Amygdala Circuit During Virtual Reality Fear Conditioning

  Up to $211KDeadline: Feb 28, 2030open

  /ABSTRACT Anxiety disorders, including generalized anxiety disorder (GAD) and post-traumatic stress disorder (PTSD), are the most prevalent mental hea...

• Measure striatal adenosine-dopamine receptors interactions: from molecule to behaviors

  Up to $201KDeadline: Jan 31, 2027open

  / Abstract Adenosine 2A receptors (A2AR) and dopamine D2 receptors (D2R) are G-protein coupled receptors (GPCRs) that are highly colocalized in the st...

• Training in Behavioral Design Interventions to Address Stigma among Men Who have Sex with Men

  Up to $81KDeadline: Feb 7, 2028open

  In Malaysia, there is a concentrated HIV epidemic among men who have sex with men (MSM) and the incidence and mortality rates are increasing, which is...

• Peripubertal Social Motivation as a Novel Risk Factor Linking Childhood Threat Exposure and Suicidal Ideation and Behavior in Preteen Girls.

  Up to $78KDeadline: May 31, 2028open

  Suicide is the second leading cause of death for youth aged 10-12. Recent data from the CDC show that girls have greater rates of STBs than boys—1 in ...

• Understanding early developmental trajectories of, and mechanisms underlying, sensory reactivity in infants at familial risk for ASD and ADHD

  Up to $74KDeadline: Aug 31, 2026open

  Individuals with autism spectrum disorder (ASD) often show altered responsivity to incoming sensory stimuli (i.e., hyper-reactivity, hypo-reactivity, ...

• Understanding the mechanisms by which vCA1 orchestrates avoidance behavior

  Up to $50KDeadline: Feb 26, 2027open

  The approach-avoid dichotomy is inherent in motivated behavior and animal survival; adaptive behavior requires these conflicting drives be appropriate...

• Perinatal depressive symptoms and infant self-regulation: Pathways through infant autonomic regulation and postnatal maternal sensitivity

  Up to $49KDeadline: Sep 4, 2026open

  /SUMMARY Offspring of mothers with depression are at threefold risk of developing depression themselves, known as the intergenerational transmission ...

• Protein phosphatase 1 isoforms, human de novo mutations and synaptic functions

  Up to $38KDeadline: Feb 29, 2028open

  Reversible phosphorylation is a critical regulatory mechanism for spine morphogenesis, synaptic transmission, long-term potentiation (LTP) and memory ...

• Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01)

  Deadline: Jun 5, 2026open

  Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01) is sponsored by National Institu...

  mental_healthpublic_healthdisabilityyouth mental healthempirically-supported practices

Where National Institute of Mental Health grants go

Recent grant recipients are concentrated in these states. Funders sometimes fund outside their primary states for high-fit projects, so don't self-eliminate solely on geography — check each opportunity's stated eligibility.

How to apply for National Institute of Mental Health grants

Most National Institute of Mental Health applications require: an organizational profile with mission and programs, a project proposal aligned with the funder's stated priorities, a project budget, and supporting attachments (IRS determination letter, board list, recent financials). Federal applicants additionally need a SAM.gov UEI and an active Grants.gov account.