National Institute of Allergy and Infectious Diseases Grants

Open National Institute of Allergy and Infectious Diseases grants

• Dissecting innate immune control of intestinal and systemic Yersinia infection

  Up to $1.0MDeadline: Feb 28, 2030open

  Infection by many pathogens leads to the formation of structures termed granulomas, organized clusters of macrophages, neutrophils, and lymphocytes, t...

• [18F]fluoromannitol: A novel imaging agent to delineate osteomyelitis in sickle cell disease

  Up to $895KDeadline: Jan 31, 2029open

  Sickle cell disease (SCD) is the most common inherited hematological disorder, affecting millions of patients worldwide and predominantly underserved ...

• Synergistic Nanobodies for Pandemic Preparedness

  Up to $876KDeadline: Jan 31, 2030open

  Betacoronaviruses (beta-CoVs), including SARS-CoV-1, MERS-CoV, and SARS-CoV-2, have reshaped our understanding of pandemic preparedness. These viruses...

• Care, Review, Assessment and Feedback Tool In Acute Respiratory infections (CRAFT-IAR)

  Up to $874KDeadline: Feb 28, 2030open

  Unnecessary antibiotic prescribing is a potentially avoidable source of iatrogenic harm, particularly in unscheduled outpatient care settings. Urgent ...

• Characterization of a novel post-transcriptional regulator in P. aeruginosa

  Up to $869KDeadline: Jan 31, 2030open

  Pseudomonas aeruginosa is an important opportunistic pathogen of humans. It is the principal cause of morbidity and mortality in people with cystic fi...

• Development of broadly neutralizing human monoclonal antibodies against henipaviruses

  Up to $830KDeadline: Jan 31, 2030open

  Henipaviruses (HNVs), including Hendra (HeV) and Nipah (NiV) viruses, are highly pathogenic agents causing severe respiratory and neurological disease...

• Bridging cell and organism scales to model viral, cell, and microenvironmental determinants of infection outcome

  Up to $812KDeadline: May 31, 2030open

  Research Project 2 (RP2) proposes to develop equation learning and model-constrained neural network frameworks to bridge between spatially explicit ce...

• Evolved cefiderocol resistance and cross protection

  Up to $795KDeadline: Jan 31, 2030open

  /ABSTRACT Pseudomonas aeruginosa (PA) causes lung infections in 44% of the ~31,000 people in the USA with cystic fibrosis (CF). PA CF lung infections ...

• Molecular details of the IgE antibody response to galactose-alpha-1,3-galactose in alpha-gal syndrome

  Up to $753KDeadline: Feb 28, 2030open

  The IgE molecule lies at the center of the pathogenesis of allergic diseases. In sensitized individuals, re-exposure to the offending allergen results...

• Mechanism of parainfluenza virus genome replication

  Up to $734KDeadline: Feb 28, 2030open

  SUMMARY The non-segmented negative strand RNA viruses (nsNSVs) include pathogens that infect humans, mammals, birds, reptiles, fish, insects, and plan...

• Biophysical and genetic approaches to uncover ventral disc contractile attachment mechanisms in Giardia

  Up to $718KDeadline: Feb 28, 2030open

  Giardia lamblia is a widespread zoonotic intestinal parasite that causes acute and chronic diarrheal disease, affecting over 280 million people annual...

• An integrated multiplexed diagnostic assay targeting fusion lipoproteins and cardiolipin for detection of treponemal and nontreponemal antibodies in syphilis patients

  Up to $692KDeadline: Jan 31, 2029open

  Syphilis cases in the US are increasing at an alarming rate and the need for a rapid diagnostic test that can quickly inform treatment and management ...

• Membrane Protein Complexes in the M. Tuberculosis Divisome: Structures and Interactions

  Up to $669KDeadline: Feb 28, 2030open

  Tuberculosis (TB) has inflicted a quarter of the worldwide population and caused 1.6 million deaths in 2021 alone. However, there have been no new cla...

• Mosquito extracellular vesicles in malaria parasite killing and immune priming

  Up to $649KDeadline: Jan 31, 2030open

  Malaria has had devastating impacts on human health and economic development throughout the world. Caused by Plasmodium parasites, the transmission of...

• Mechanisms of STAT1 and STAT3 canonical and persistent activation in physiology and disease

  Up to $639KDeadline: Feb 28, 2030open

  Summary Rapid plasma membrane-to-nucleus relocalization of Signal Transducer and Activator of Transcription (STAT) family members upon cytokines stimu...

• Structural studies of the OrfX-type progenitor toxin complex of botulinum neurotoxin

  Up to $617KDeadline: Feb 28, 2030open

  Botulinum neurotoxins (BoNTs) are produced by anaerobic bacteria of the genus Clostridium, which are the causative agents of the neuroparalytic diseas...

• Metabolic and epigenetic regulation of skin Tregs

  Up to $598KDeadline: Feb 28, 2030open

  CD4+Foxp3+ regulatory T cells (Tregs) maintain immune tolerance and suppress autoimmunity. Recent studies reveal that Tregs not only reside in seconda...

• Immunobiology of a novel human DAMP receptor, its murine homolog, & their ligand

  Up to $578KDeadline: Jan 31, 2030open

  The immune system has evolved mechanisms to recognize and respond to cell injury and this response contributes in important ways to both health and di...

• A single biosensors for the simultaneous molecular detection of HIV and Hepatitis B and C viruses at resource-limited settings

  Up to $538KDeadline: Feb 29, 2028open

  Despite advancements in healthcare, the diagnosis of HIV, HCV and HBV remain poor globally, with a high percentage of undiagnosed and untreated cases....

• Optimization of UltraPCR for detection of and assessment of treatment outcomes in Trypanosoma cruzi infection

  Up to $505KDeadline: Feb 28, 2030open

  Infection with the protozoan parasite Trypanosoma cruzi is generally controlled but often not eliminated by host immune responses. In humans and many ...

Where National Institute of Allergy and Infectious Diseases grants go

Recent grant recipients are concentrated in these states. Funders sometimes fund outside their primary states for high-fit projects, so don't self-eliminate solely on geography — check each opportunity's stated eligibility.

How to apply for National Institute of Allergy and Infectious Diseases grants

Most National Institute of Allergy and Infectious Diseases applications require: an organizational profile with mission and programs, a project proposal aligned with the funder's stated priorities, a project budget, and supporting attachments (IRS determination letter, board list, recent financials). Federal applicants additionally need a SAM.gov UEI and an active Grants.gov account.