National Institute of Biomedical Imaging and Bioengineering Grants

Open National Institute of Biomedical Imaging and Bioengineering grants

• SmartStim, a novel implantable neuromodulation system to cure chronic pain.

  Up to $3.5MDeadline: Jul 31, 2028open

  /Abstract Chronic pain without apparent tissue damage is characterized by central sensitization at the level of spinal cord and brain, which often res...

• Surgical pathology-enabled augmented reality for head and neck tumor resection with deformation modeling

  Up to $2.2MDeadline: Jul 31, 2029open

  The importance of achieving a clear margin in head and neck surgery is emphasized by the fact that a positive margin status increases all-cause mortal...

• Combinatorial Engineering of Multicellular Synthetic Immunotherapy Systems

  Up to $1.4MDeadline: Jul 31, 2028open

  /Abstract: Immune cells—T cells, natural killer (NK) cells, or macrophages—engineered to express synthetic receptors have emerged as powerful anti-can...

• De novo design and engineering of biological error correction

  Up to $1.1MDeadline: Jul 31, 2030open

  / ABSTRACT Biological systems have evolved a remarkable ability of error correction in processes essential for life. Non- equilibrium mechanisms of ki...

• Integrating Clinical Knowledge: A Multimodal AI System for Reliable Head CT Understanding and Interpretation

  Up to $742KDeadline: May 31, 2029open

  SUMMARY The field of radiology is undergoing a significant transformation with the integration of artificial intelligence (AI), particularly in head c...

• 1 mm resolution single-photon spectral imaging of the brain

  Up to $728KDeadline: Jul 31, 2028open

  In this proposed research project, we seek to develop an advanced brain SPECT system that offers a unique hyperspectral imaging capability substantiat...

• Direct Methylation with [11C]CO2 for Production of Radiopharmaceuticals

  Up to $700KDeadline: Jul 31, 2028open

  Positron Emission Tomography (PET) is an imaging modality that can be used to visualize and quantify functional changes and the distribution of molecu...

• Robust and Interpretable Multi-modal AI/ML for Precision Medicine

  Up to $697KDeadline: Jun 30, 2029open

  Biomedical research increasingly leverages multi-modal data, including genomic, multi-omics, medical imaging, and clinical narratives, to advance prec...

• Transcranial Doppler array for automated ultrasound emboli detection with deep learning

  Up to $678KDeadline: Mar 31, 2030open

  /Abstract Stroke affects nearly 800,000 Americans each year. Assigning the risk of a future stroke is feasible based on established risk factors, such...

• Leveraging Multi-Modal AI for Selective Use of Ultrasound in Breast Cancer Screening

  Up to $672KDeadline: May 31, 2029open

  Supplemental breast screening ultrasound is recommended for women with dense breasts, accounting for nearly half of U.S. women over age 40. While brea...

• Single-use Microfluidic Device for Radiopharmaceutical Production

  Up to $663KDeadline: Feb 28, 2029open

  Radiopharmaceuticals (RPs) are essential linchpins of cancer diagnosis, staging, and therapy. For diagnosis, the sensitivity and quantitative nature o...

• Advancing Neurosymbolic AI for Smart and Trustworthy Healthcare

  Up to $653KDeadline: May 31, 2029open

  Artificial intelligence (AI) is poised to transform healthcare, particularly in clinical decision support for treatment selection in a range of diseas...

• A Deep Learning-based Assessment Pipeline for Peripherally Inserted Central Catheters (PICCs) on Pediatric Radiographs

  Up to $642KDeadline: Jul 31, 2028open

  Peripherally inserted central catheters (PICCs) have become an integral part of the complex intensive care of critically ill patients in pediatric int...

• Synthetic Compartments to Rewire Inflammatory Signaling and Augment Immune Cell Function

  Up to $617KDeadline: Jul 31, 2026open

  Engineered immunotherapies harness the power of the immune system to combat diseases and to attack specified targets, such as cancer cells. While thei...

• Cell Morphology-guided, Scalable and Controllable Molecule Design via Generative AI

  Up to $617KDeadline: Jul 31, 2028open

  This project aims to advance phenotypic drug discovery (PDD) by developing a generative AI-driven platform for innovative, cell morphology-guided, sca...

• Quantitative Phase Imaging Meta-Sensors for Noninvasive Real-Time Capillaroscopy

  Up to $613KDeadline: Jul 31, 2028open

  Quantitative phase imaging is a powerful modality of widefield microscopy that allows visualizing transparent biological cells and extracting importan...

• The Development of antigent-presentation modulating nanoparticles (APM-NPs) to improve immunization

  Up to $599KDeadline: May 31, 2029open

  There is a need for a new immune engineering platform technology to engineer T cell responses and direct their function for diseases spanning from vir...

• Pragmatic and automated pressure injury detection across a heterogeneous patient population

  Up to $599KDeadline: Jul 31, 2029open

  The incidence rates of pressure injuries (PrIs) are on the rise, intensifying the workload for nurses, leading to bad outcomes for patients, and incre...

• Sensing Collimator Technology for Ultrasensitive SPECT Imaging of Targeted Radiopharmaceutical Therapies

  Up to $598KDeadline: Jul 31, 2029open

  This application addresses critically unmet needs in the field of targeted radiopharmaceutical therapy, an emerging treatment paradigm for metastatic ...

• Engineering Technologies for Acute Trauma Care

  Up to $580KDeadline: Jan 31, 2029open

  Trauma-related injuries, such as from motor vehicle accidents, accidental falls or acts of violence, are the 3rd leading cause of death in the United ...

Where National Institute of Biomedical Imaging and Bioengineering grants go

Recent grant recipients are concentrated in these states. Funders sometimes fund outside their primary states for high-fit projects, so don't self-eliminate solely on geography — check each opportunity's stated eligibility.

How to apply for National Institute of Biomedical Imaging and Bioengineering grants

Most National Institute of Biomedical Imaging and Bioengineering applications require: an organizational profile with mission and programs, a project proposal aligned with the funder's stated priorities, a project budget, and supporting attachments (IRS determination letter, board list, recent financials). Federal applicants additionally need a SAM.gov UEI and an active Grants.gov account.