North Carolina Grants

Top North Carolina grants right now

• Small Business Infrastructure Grant Program

  North Carolina Department of CommerceUp to $55Mopen

  Small Business Infrastructure Grant Program is sponsored by North Carolina Department of Commerce. Provides grants to local governments in western Nor...

  small_businessresiliencerural_development

• Leveraging Artificial Intelligence to Predict Mental Health Risk among Youth Presenting to Rural Primary Care Clinics

  Up to $15MDeadline: Sep 9, 2029open

  This study, in response to RFA-MH-25-195, aims to enhance, deploy, and rigorously validate the Duke Predictive Model of Adolescent Mental Health (Duke...

• NHLBI CATALYZE PRECLINICAL SERVICES: PROJECTS YR. 4 - TASK ORDER 5

  Up to $10.0MDeadline: Sep 28, 2026open

  The NHLBI has a need to transition the Catalyze Coordinating Center (hereinafter referred to as CatCC) to a contract mechanism in order to maintain a ...

• CTSA UM1 at Duke University

  National Center for Advancing Translational SciencesUp to $9.9MDeadline: Jul 31, 2032open

  The mission of the Duke Clinical and Translational Science Institute (CTSI), home to the Clinical and Translational Science Award (CTSA) since 2006, i...

• Moderation of Aging Trajectories of Cognition and Neuropathology by Diet Composition in Middle-aged Nonhuman Primates

  Up to $6.4MDeadline: Sep 14, 2029open

  Diet composition potently modulates trajectories of brain aging. Intake of a "Mediterranean" diet including fruit and vegetables, fish, and healthy fa...

• From Data to Action: Capturing Meaningful Outcomes in Autism Through Harmonized Data

  Up to $4.3MDeadline: Sep 28, 2028open

  There are more autistic adults in the service system than ever before, and this number is estimated to increase by as much as 300% by 2030. Outcomes f...

• Proto-OKN Theme 2: OKN-Fabric

  Up to $4.1MDeadline: Sep 30, 2027open

  Modern information systems struggle to connect related data across organizations, making it difficult to solve complex national challenges that requir...

• Modeling autism-associated gene-by-environment interactions in human brain organoids

  Up to $3.9MDeadline: Sep 28, 2028open

  Genetic studies have been highly successful in identifying causal factors associated with autism spectrum disorders (ASD). However, current genetic as...

• 1/2 PREEMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

  Up to $3.9MDeadline: Jun 30, 2027open

  Failure to detect and treat atherosclerosis in younger adults worsens cardiovascular morbidity and mortality. Current strategies of assigning preventi...

• Jackson Heart Study (JHS) Coordinating Center: Task Area A - Core Study Operations

  Up to $3.8MDeadline: Sep 14, 2035open

  The Jackson Heart Study (JHS) (https://www.jacksonheartstudy.org/) initiated in 1998 is a longitudinal investigation of genetic and environmental risk...

• Combating Related Epidemics in HCV through Simplified Testing and Treatment (CREST)

  Up to $3.4MDeadline: Aug 31, 2030open

  /ABSTRACT The opioid epidemic is a primary driver of new hepatitis C virus (HCV) infections, especially among younger (

• Development of Therapeutic Candidates for Antibiotic Resistant Bacteria

  Up to $3.3MDeadline: Feb 7, 2029open

  To support the advanced development of candidate therapeutics for antibiotic resistant pathogens. The supported research and development activities wi...

• Immunomodulation in AAV gene therapy

  Up to $3.2MDeadline: Jul 31, 2029open

  Recombinant AAV vectors have emerged as promising gene delivery vehicles in the treatment of monogenic disorders. With 6 different FDA approved AAV-ba...

• Developing a bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza response

  National Institute of Allergy and Infectious DiseasesUp to $3.2MDeadline: Jul 31, 2029open

  / ABSTRACT Our goal is to understand how the lung microbiome regulates influenza virus infection response by developing a 3D in vitro bioprinted platf...

• Effect of caloric restriction on aging biomarkers, frailty, and multimorbidity in older adults

  National Institute on AgingUp to $3.2MDeadline: May 31, 2030open

  /Abstract Obesity is associated with poor quality of life and reduced lifespan and healthspan – the period of time free of multiple chronic diseases a...

• Real world use of anti-obesity medications to treat adolescent obesity: moving beyond the clinical trial

  Up to $3.1MDeadline: Jul 31, 2029open

  /ABSTRACT One in five US adolescents have obesity, making pediatric obesity a significant public health problem. Safe and effective treatment options ...

• RNA Programmable and Scalable Brain Cell Type Tools Across Vertebrates

  Up to $3.1MDeadline: Feb 28, 2030open

  A major goal in neuroscience is to analyze neural circuit structure and function in diverse brain regions and species with cell type resolution. Achie...

• PFAS exposure is detrimental to placental function and fetal development by disrupting mitochondrial function and metabolism

  Up to $3.1MDeadline: Sep 4, 2029open

  Per- and poly-fluoroalkyl substances (PFAS) exposure is widespread and has sparked major concerns about health impacts in highly contaminated communit...

• CLINICAL RESEARCH OPERATIONS AND MANAGEMENT SUPPORT (CROMS)

  Up to $3.1MDeadline: Sep 29, 2030open

  The objective of this contract renewal is to continue operations and management support services for clinical research studies supported by the Nation...

• Discovery of Gene-by-Air Pollution Interactions in Respiratory Disease using Genetically Diverse Mice with Validation in Humans

  Up to $3.1MDeadline: Sep 18, 2029open

  Our goal is to identify gene-environment interactions (GxE) with acute and chronic exposure to the ambient air pollutant ozone (O3) that contribute to...

Where North Carolina grants come from

• Federal sources — Grants.gov, NIH RePORTER, and SAM.gov, filtered for opportunities that fund work in North Carolina.
• North Carolina state portal — state-administered grant programs, including pass-through federal dollars and state-only appropriations.
• Foundations — community foundations and private foundations active in North Carolina, drawn from IRS Form 990 filings and curated foundation directories.
• Corporate giving — a curated set of corporate philanthropy programs that explicitly fund North Carolina-based work.

Listings are refreshed daily and stale data is flagged. Local funders missing from your area? You can request ZIP-level coverage after creating a free account.

Qualify North Carolina grants before you write

Most of the time it takes to win a grant isn't writing — it's research and qualifying. Before you commit a week to a full proposal, qualify the opportunity with a 1–2 page Letter of Inquiry. Our guide walks through the structure that gets a yes: