Top Grant Opportunities

Preview the top 100 highest-funded grants from our database of 100,032+ opportunities. No account needed.

Want the full database with AI-powered matching, proposal drafting, and funder intelligence? Start your free trial →

Listings refreshed daily from Grants.gov, state portals, and curated foundation sources.

100,032
Open grants
0
Forecasted
51
States covered
25,844
scope:national

100 grants found

Page 1 of 5

Small Business Infrastructure Grant Program

North Carolina Department of Commerce
Up to $55.0M
North Carolinasmall_businessresiliencerural_development

Small Business Infrastructure Grant Program is sponsored by North Carolina Department of Commerce. Provides grants to local governments in western Nor...

See full details — Sign up free

Leveraging Artificial Intelligence to Predict Mental Health Risk among Youth Presenting to Rural Primary Care Clinics

Due Sep 9, 2029
$15.0M - $15.0M
DURHAM, NC

This study, in response to RFA-MH-25-195, aims to enhance, deploy, and rigorously validate the Duke Predictive Model of Adolescent Mental Health (Duke...

See full details — Sign up free

NHLBI CATALYZE PRECLINICAL SERVICES: PROJECTS YR. 4 - TASK ORDER 5

Due Sep 28, 2026
$10.0M - $10.0M
RESEARCH TRIANGLE PARK, NC

The NHLBI has a need to transition the Catalyze Coordinating Center (hereinafter referred to as CatCC) to a contract mechanism in order to maintain a ...

See full details — Sign up free

CTSA UM1 at Duke University

National Center for Advancing Translational Sciences·Due Jul 31, 2032
$9.9M - $9.9M
DURHAM, NC

The mission of the Duke Clinical and Translational Science Institute (CTSI), home to the Clinical and Translational Science Award (CTSA) since 2006, i...

See full details — Sign up free

HIV and Other Infectious Diseases Clinical Research Support Services (CRSS)

National Institute of Allergy and Infectious Diseases·Due Aug 14, 2026
$8.7M - $8.7M
WILMINGTON, NC

In support of NIAID Division of AIDS (DAIDS) activities, this contract provides a broad range of clinical, laboratory, training and related services t...

See full details — Sign up free

Want AI-powered matching?

GrantMind scores every grant against your organization's profile. Start your 7-day free trial.

Start free trial

Moderation of Aging Trajectories of Cognition and Neuropathology by Diet Composition in Middle-aged Nonhuman Primates

Due Sep 14, 2029
$6.4M - $6.4M
WINSTON-SALEM, NC

Diet composition potently modulates trajectories of brain aging. Intake of a "Mediterranean" diet including fruit and vegetables, fish, and healthy fa...

See full details — Sign up free

From Data to Action: Capturing Meaningful Outcomes in Autism Through Harmonized Data

Due Sep 28, 2028
$4.3M - $4.3M
CHAPEL HILL, NC

There are more autistic adults in the service system than ever before, and this number is estimated to increase by as much as 300% by 2030. Outcomes f...

See full details — Sign up free

Proto-OKN Theme 2: OKN-Fabric

Due Sep 30, 2027
$4.1M - $4.1M
CHAPEL HILL, NC

Modern information systems struggle to connect related data across organizations, making it difficult to solve complex national challenges that requir...

See full details — Sign up free

Modeling autism-associated gene-by-environment interactions in human brain organoids

Due Sep 28, 2028
$3.9M - $3.9M
CHAPEL HILL, NC

Genetic studies have been highly successful in identifying causal factors associated with autism spectrum disorders (ASD). However, current genetic as...

See full details — Sign up free

1/2 PREEMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

Due Jun 30, 2027
$3.9M - $3.9M
DURHAM, NC

Failure to detect and treat atherosclerosis in younger adults worsens cardiovascular morbidity and mortality. Current strategies of assigning preventi...

See full details — Sign up free

Want AI-powered matching?

GrantMind scores every grant against your organization's profile. Start your 7-day free trial.

Start free trial

Jackson Heart Study (JHS) Coordinating Center: Task Area A - Core Study Operations

Due Sep 14, 2035
$3.8M - $3.8M
WINSTON-SALEM, NC

The Jackson Heart Study (JHS) (https://www.jacksonheartstudy.org/) initiated in 1998 is a longitudinal investigation of genetic and environmental risk...

See full details — Sign up free

Combating Related Epidemics in HCV through Simplified Testing and Treatment (CREST)

Due Aug 31, 2030
$3.4M - $3.4M
DURHAM, NC

/ABSTRACT The opioid epidemic is a primary driver of new hepatitis C virus (HCV) infections, especially among younger (

See full details — Sign up free

Development of Therapeutic Candidates for Antibiotic Resistant Bacteria

Due Feb 7, 2029
$3.3M - $3.3M
Morrisville, NC

To support the advanced development of candidate therapeutics for antibiotic resistant pathogens. The supported research and development activities wi...

See full details — Sign up free

Immunomodulation in AAV gene therapy

Due Jul 31, 2029
$3.2M - $3.2M
DURHAM, NC

Recombinant AAV vectors have emerged as promising gene delivery vehicles in the treatment of monogenic disorders. With 6 different FDA approved AAV-ba...

See full details — Sign up free

Developing a bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza response

National Institute of Allergy and Infectious Diseases·Due Jul 31, 2029
$3.2M - $3.2M
DURHAM, NC

/ ABSTRACT Our goal is to understand how the lung microbiome regulates influenza virus infection response by developing a 3D in vitro bioprinted platf...

See full details — Sign up free

Want AI-powered matching?

GrantMind scores every grant against your organization's profile. Start your 7-day free trial.

Start free trial

Effect of caloric restriction on aging biomarkers, frailty, and multimorbidity in older adults

National Institute on Aging·Due May 31, 2030
$3.2M - $3.2M
WINSTON-SALEM, NC

/Abstract Obesity is associated with poor quality of life and reduced lifespan and healthspan – the period of time free of multiple chronic diseases a...

See full details — Sign up free

Real world use of anti-obesity medications to treat adolescent obesity: moving beyond the clinical trial

Due Jul 31, 2029
$3.1M - $3.1M
DURHAM, NC

/ABSTRACT One in five US adolescents have obesity, making pediatric obesity a significant public health problem. Safe and effective treatment options ...

See full details — Sign up free

RNA Programmable and Scalable Brain Cell Type Tools Across Vertebrates

Due Feb 28, 2030
$3.1M - $3.1M
DURHAM, NC

A major goal in neuroscience is to analyze neural circuit structure and function in diverse brain regions and species with cell type resolution. Achie...

See full details — Sign up free

PFAS exposure is detrimental to placental function and fetal development by disrupting mitochondrial function and metabolism

Due Sep 4, 2029
$3.1M - $3.1M
DURHAM, NC

Per- and poly-fluoroalkyl substances (PFAS) exposure is widespread and has sparked major concerns about health impacts in highly contaminated communit...

See full details — Sign up free

CLINICAL RESEARCH OPERATIONS AND MANAGEMENT SUPPORT (CROMS)

Due Sep 29, 2030
$3.1M - $3.1M
Durham, NC

The objective of this contract renewal is to continue operations and management support services for clinical research studies supported by the Nation...

See full details — Sign up free

Ready to win grants, not just browse them?

The Grant Board shows you what's out there. GrantMind, the system, helps you actually win: find the right funders for your mission, qualify what's worth chasing, draft proposals tuned to each funder, and track every deadline through to funded dollars.

Start 7-day free trial

7-day free trial. No credit card required. Cancel anytime.

Newsletter

Top grants of the week, in your inbox

Five hand-picked grants every Monday — the biggest awards, the soonest deadlines, and the freshest opportunities. Free, one-click unsubscribe.

Free · one email a week · unsubscribe anytime