Substance Use & Recovery Grants

Top opportunities

• Hepatitis C Elimination Initiative Pilot

  U.S. Department of Health and Human Services (HHS) / Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $100Mopen

  Hepatitis C Elimination Initiative Pilot is sponsored by U.S. Department of Health and Human Services (HHS) / Substance Abuse and Mental Health Servic...

  health_disparitiesinfectious_diseasepublic_healthhepatitis chcv

• Development of a national laboratory to improve the monitoring of substances discharged into waters and the quality of drinking water - Stage II

  Up to $32MDeadline: Dec 31, 2026open

  Development of a virtual laboratory at national level, which collects analysis data from 99 laboratories for monitoring substances and indicators in w...

• Cooperative Agreements for States and Territories to Improve Local 988 Capacity

  Substance Abuse and Mental Health Services AdminisUp to $20MDeadline: Jul 17, 2026open

  Max award: $20,195,467 Eligibility: Eligibility is limited to State and territorial government agencies, including the District of Columbia; Guam; th...

• Cooperative Agreements for States and Territories to Improve Local 988 Capacity

  Substance Abuse and Mental Health Services AdminisUp to $20MDeadline: Jul 17, 2026open

  The purpose of this program is to improve state and territory response to all 988 contacts (including calls, chats, and texts) originating in the stat...

• Community Mental Health Services Block Grant (Supplemental Funding for Housing Capacity)

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $19Mopen

  Community Mental Health Services Block Grant (Supplemental Funding for Housing Capacity) is sponsored by Substance Abuse and Mental Health Services Ad...

  health_disparitiesmental_healthmental healthhomelessnesshousing

• National Center for Child Traumatic Stress - Category 1

  Substance Abuse and Mental Health Services AdminisUp to $8.0MDeadline: Jul 13, 2026open

  The purpose of the National Child Traumatic Stress Initiative - Category I National Center for Child Traumatic Stress (NCCTS) program is to create/mai...

• National Center for Child Traumatic Stress - Category 1

  Substance Abuse and Mental Health Services AdminisUp to $8.0MDeadline: Jul 13, 2026open

  Max award: $8,000,000 Eligibility: Eligibility is statutorily limited to domestic public and private non-profit entities.

• High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional) RFA-DA-25-060

  National Institute on Drug Abuse (NIDA), NIHUp to $7.5MDeadline: Aug 14, 2026open

  High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional) RFA-DA-25-060 is sponsored by National Institute on Drug Abuse (NIDA), NIH....

  health_disparitiesinfectious_diseasesubstance_abusehivsubstance use

• Cohort Studies of HIV/AIDS and Substance Use in Miami

  Up to $7.4MDeadline: Jun 30, 2030open

  This is a proposal for the continuation of the well-characterized Miami Adult Studies on HIV (MASH) cohort of middle-to-old, aged people living with a...

• Services Grant Program for Residential Treatment for Pregnant and Postpartum Women

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $5.3Mopen

  Services Grant Program for Residential Treatment for Pregnant and Postpartum Women is sponsored by Substance Abuse and Mental Health Services Administ...

  substance_abusematernal_healthmental_healthpublic_healthtribal_health

• Support to Communities: Fostering Opioid Recovery Through Workforce Development

  U.S. Department of LaborUp to $5.0Mopen

  Support to Communities: Fostering Opioid Recovery Through Workforce Development is a competitive grant from the U.S. Department of Labor that funds tr...

  health_disparitiespublic_healthsubstance_abuseworkforce_developmentopioid recovery

• Monitoring the quality of the country's surface water Identification of priority substances and specific pollutants

  Up to $4.3MDeadline: Dec 31, 2029open

  The General Chemical State Laboratory (GCSL) is one of the operating bodies of the National Monitoring Network for the qualitative and quantitative st...

• EPA Brownfields Cleanup Grants

  U.S. Environmental Protection Agency (EPA)Up to $4.0Mopen

  EPA Brownfields Cleanup Grants is sponsored by U.S. Environmental Protection Agency (EPA). Offers funding for cleanup activities at brownfield sites t...

  brownfieldswater_qualityland_conservationenvironmental_justicebrownfield cleanup

• Collaborative Research: FEC: Tri-State Collaborative for Defluorination of Per- and Polyfluoroalkyl Substances

  Up to $3.6MDeadline: Aug 31, 2029open

  Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals, and certain legacy PFAS may pose health and environmental risks due to the strong ...

• Assertive Community Treatment (ACT) Grant Program

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $3.4Mopen

  Assertive Community Treatment (ACT) Grant Program is sponsored by Substance Abuse and Mental Health Services Administration (SAMHSA). Supports the est...

  mental_healthpublic_healthcommunity_developmenthealth_disparitiesmental health

• Safety Through Recovery, Engagement, and Evidence-Based Treatment and Support

  Substance Abuse and Mental Health Services AdminisUp to $3.0MDeadline: Jul 17, 2026open

  Max award: $3,000,000 Eligibility: Eligibility is limited to political sub-divisions of States (cities, counties), Indian tribes, and tribal organiza...

• Safety Through Recovery, Engagement, and Evidence-Based Treatment and Support

  Substance Abuse and Mental Health Services AdminisUp to $3.0MDeadline: Jul 17, 2026open

  The purpose of this program is to support comprehensive, street-based engagement, treatment, and recovery support services for individuals who are hom...

• HEAL Initiative: Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  National Institutes of Health (NIH)Up to $3.0MDeadline: Aug 21, 2028open

  HEAL Initiative: Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) is sponsor...

  substance_abuse

• Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  Up to $3.0MDeadline: Aug 21, 2028open

  Max award: $3,000,000 Eligibility: Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Comm...

• Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  National Institutes of HealthUp to $3.0MDeadline: Aug 21, 2028open

  The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions ...

What's included in substance use & recovery grants

We track grants tagged with the following keywords. If your work uses different language internally, AI mission-fit search (available after signup) will catch the conceptual matches that exact-keyword filtering misses.

How GrantMind sources these grants

• Federal sources — Grants.gov, NIH RePORTER, and SAM.gov, filtered for opportunities tagged or thematically aligned with substance use & recovery.
• State portals — state-administered programs across all 50 states and D.C.
• Foundations — community and private foundations active in this category, drawn from IRS Form 990 filings and curated foundation directories.
• Corporate giving — a curated set of corporate philanthropy programs.

Make these grants count

The leverage point isn't writing more proposals — it's qualifying funders before you write. A 1–2 page Letter of Inquiry tells you in days whether a foundation is going to fund you, instead of forty hours from now. Our guide walks through the structure that gets a yes: