Substance Use & Recovery Grants

Top opportunities

• Hepatitis C Elimination Initiative Pilot

  U.S. Department of Health and Human Services (HHS) / Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $100Mopen

  Hepatitis C Elimination Initiative Pilot is sponsored by U.S. Department of Health and Human Services (HHS) / Substance Abuse and Mental Health Servic...

  health_disparitiesinfectious_diseasepublic_healthhepatitis chcv

• Development of a national laboratory to improve the monitoring of substances discharged into waters and the quality of drinking water - Stage II

  Up to $32MDeadline: Dec 31, 2026open

  Development of a virtual laboratory at national level, which collects analysis data from 99 laboratories for monitoring substances and indicators in w...

• Community Mental Health Services Block Grant (Supplemental Funding for Housing Capacity)

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $19Mopen

  Community Mental Health Services Block Grant (Supplemental Funding for Housing Capacity) is sponsored by Substance Abuse and Mental Health Services Ad...

  health_disparitiesmental_healthmental healthhomelessnesshousing

• Service Members, Veterans, and their Families (SMVF) Grant Program

  HHS Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $10Mopen

  SAMHSA grants to expand and improve behavioral health treatment, crisis response, and supportive services for service members, veterans, and their fam...

  discover:veterans servicesfit_score:90

• Cohort Studies of HIV/AIDS and Substance Use in Miami

  Up to $7.4MDeadline: Jun 30, 2030open

  This is a proposal for the continuation of the well-characterized Miami Adult Studies on HIV (MASH) cohort of middle-to-old, aged people living with a...

• Services Grant Program for Residential Treatment for Pregnant and Postpartum Women

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $5.3Mopen

  Services Grant Program for Residential Treatment for Pregnant and Postpartum Women is sponsored by Substance Abuse and Mental Health Services Administ...

  substance_abusematernal_healthmental_healthpublic_healthtribal_health

• Support to Communities: Fostering Opioid Recovery Through Workforce Development

  U.S. Department of LaborUp to $5.0Mopen

  Support to Communities: Fostering Opioid Recovery Through Workforce Development is a competitive grant from the U.S. Department of Labor that funds tr...

  health_disparitiespublic_healthsubstance_abuseworkforce_developmentopioid recovery

• Monitoring the quality of the country's surface water Identification of priority substances and specific pollutants

  Up to $4.3MDeadline: Dec 31, 2029open

  The General Chemical State Laboratory (GCSL) is one of the operating bodies of the National Monitoring Network for the qualitative and quantitative st...

• EPA Brownfields Cleanup Grants

  U.S. Environmental Protection Agency (EPA)Up to $4.0Mopen

  EPA Brownfields Cleanup Grants is sponsored by U.S. Environmental Protection Agency (EPA). Offers funding for cleanup activities at brownfield sites t...

  brownfieldswater_qualityland_conservationenvironmental_justicebrownfield cleanup

• Collaborative Research: FEC: Tri-State Collaborative for Defluorination of Per- and Polyfluoroalkyl Substances

  Up to $3.6MDeadline: Aug 31, 2029open

  Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals, and certain legacy PFAS may pose health and environmental risks due to the strong ...

• Assertive Community Treatment (ACT) Grant Program

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $3.4Mopen

  Assertive Community Treatment (ACT) Grant Program is sponsored by Substance Abuse and Mental Health Services Administration (SAMHSA). Supports the est...

  mental_healthpublic_healthcommunity_developmenthealth_disparitiesmental health

• Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  Up to $3.0MDeadline: Aug 21, 2028open

  Max award: $3,000,000 Eligibility: Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Comm...

• Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  National Institutes of HealthUp to $3.0MDeadline: Aug 21, 2028open

  The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions ...

• HEAL Initiative: Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  National Institutes of Health (NIH)Up to $3.0MDeadline: Aug 21, 2028open

  HEAL Initiative: Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) is sponsor...

  substance_abuse

• Children's Mental Health Initiative

  Substance Abuse and Mental Health Services AdministrationUp to $3.0Mopen

  Children's Mental Health Initiative is sponsored by Substance Abuse and Mental Health Services Administration. Match reasons: Matches your focus: "me...

  discover:mental healthfit_score:46

• Safety Through Recovery, Engagement, and Evidence-based Treatment and Support (STREETS)

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $3.0Mopen

  Funds multisector, state-of-the-art care systems for people who are homeless and have substance use disorders, serious mental illness, or co-occurring...

  discover:disability servicesfit_score:86

• CASCADE: A North Carolina cohort to address the cascading effects of the HIV and substance use syndemic

  Up to $2.5MDeadline: Jul 31, 2030open

  The US Deep South bears the highest burden of HIV, and the South is lagging behind in achieving Ending the HIV Epidemic (EHE) goals. People who use dr...

• Community Mental Health Centers (CMHC) Grant Program

  Substance Abuse and Mental Health Services Administration (SAMHSA)Up to $2.5Mopen

  Community Mental Health Centers (CMHC) Grant Program is sponsored by Substance Abuse and Mental Health Services Administration (SAMHSA). This opportun...

  mental_healthpublic_healthcommunity mental healthbehavioral healthmental health services

• A binational cohort of the intersection between substance use, HIV, and associated comorbidities among people who inject drugs in San Diego, CA

  Up to $2.4MDeadline: May 31, 2030open

  We will prospectively study the intersection between substance use, HIV and related co-morbidities in a cohort of people who use drugs (PWUD) in San D...

• Enhancing Access to Timely Research to Prevent HIV Transmission and Effectively Treat Substance Use

  Up to $2.4MDeadline: Jun 30, 2029open

  The purpose of this proposed Avenir Award is to achieve widespread population health improvements in preventing HIV transmission and overdose amongst ...

What's included in substance use & recovery grants

We track grants tagged with the following keywords. If your work uses different language internally, AI mission-fit search (available after signup) will catch the conceptual matches that exact-keyword filtering misses.

How GrantMind sources these grants

• Federal sources — Grants.gov, NIH RePORTER, and SAM.gov, filtered for opportunities tagged or thematically aligned with substance use & recovery.
• State portals — state-administered programs across all 50 states and D.C.
• Foundations — community and private foundations active in this category, drawn from IRS Form 990 filings and curated foundation directories.
• Corporate giving — a curated set of corporate philanthropy programs.

Make these grants count

The leverage point isn't writing more proposals — it's qualifying funders before you write. A 1–2 page Letter of Inquiry tells you in days whether a foundation is going to fund you, instead of forty hours from now. Our guide walks through the structure that gets a yes: