Top Grant Opportunities

Preview the top 100 highest-funded grants from our database of 100,032+ opportunities. No account needed.

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Listings refreshed daily from Grants.gov, state portals, and curated foundation sources.

100,032
Open grants
0
Forecasted
51
States covered
25,844
scope:national

100 grants found

Page 1 of 5

ExpandQISE: Track 2: Quantum Materials Institute: 2D Materials, heterostructures and metasurfaces for compact, efficient entangled photon-pair generation for quantum communications

Due Sep 30, 2029
$5.0M - $5.0M
RAPID CITY, SD

This Expanding Capacity in Quantum Information Science and Engineering (ExpandQISE) project establishes a Quantum Materials Institute at the South Dak...

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NRT: Training Scientists to Solve Biofilm Challenges Using Artificial Intelligence and Smart Materials

Due Aug 31, 2030
$3.0M - $3.0M
RAPID CITY, SD

This National Science Foundation Research Traineeship (NRT) award to the South Dakota School of Mines and Technology, in collaboration with the Univer...

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ICE-TI: Maka Kin Awayankapi (Stewards of Earth)

Due May 31, 2030
$2.3M - $2.3M
KYLE, SD

A goal of the Tribal Colleges and Universities Program (TCUP) is to increase the science, technology, engineering and mathematics (STEM) instructional...

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Collaborative Research: FEC: Establishing Infrastructure for AI-Driven Discovery of Small Molecules to Combat Antibiotic Resistance, Biofilms, and Aflatoxin Contamination

Due Jul 31, 2029
$2.2M - $2.2M
BROOKINGS, SD

This project will develop methods to discover and design small molecules that control harmful microbes, prevent microbial-induced infrastructure deter...

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EPSCoR Graduate Fellowship Program (EGFP): Enhancing Development of Innovative Materials for Agriculture, Human Health, and Quantum Science

Due Jun 30, 2028
$1.9M - $1.9M
RAPID CITY, SD

The National Science Foundation (NSF) EPSCoR Graduate Fellowship Program (EGFP) supports EGFP designated institutions and programs in EPSCoR jurisdict...

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Equipment: MRI: Track 1 Acquisition of a Scanning Transmission Electron Microscope for Materials Research at the South Dakota School of Mines and Technology

Due Jul 31, 2027
$1.4M - $1.4M
RAPID CITY, SD

The project involves acquisition of a modern field emission scanning transmission electron microscope (FE-STEM) in support of nanoscale investigations...

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Beginnings: Dakota Biotechnology Rural Workforce Development Program

Due Sep 30, 2028
$998K - $998K
YANKTON, SD

The Dakota Biotechnology Rural Workforce Development Program is responsive to a regional workforce need by enabling current STEM students and recent S...

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CAREER: Discovery of Composition-Enriched Cosmic Ray Anisotropy with the IceCube Neutrino Observatory

Due Jun 30, 2030
$900K - $900K
RAPID CITY, SD

Cosmic rays, which are mostly made up of atomic nuclei, carry energies that far exceed what we can achieve with our human-made accelerators. Despite t...

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Dual Effects of Endocannabinoid Modulation in Nociception

Due Jun 30, 2027
$750K - $750K
VERMILLION, SD

Pain is a complex physiological and behavioral process that is still poorly understood. One example of our lack of understanding how pain works is the...

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Collaborative Research: E-RISE RII: BioNitrogen Economy Research Center

Due Jul 31, 2028
$747K - $747K
KYLE, SD

The BioNitrogen Economy Research Center (BNERC) will build state-wide research capacity focused on biological nitrogen fixation and its practical appl...

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Equipment: MRI: Track 1 Acquisition of Microbioreactor for Advancing Biological, Environmental, and Biomanufacturing Research

Due Aug 31, 2028
$687K - $687K
RAPID CITY, SD

An award is being made to South Dakota School of Mines and Technology to enable the acquisition of the BioLector XTM microbioreactor system. This syst...

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Elucidating spatiotemporal dynamics of nascent extracellular matrix in response to platinum treatment in ovarian cancer

Due Apr 30, 2030
$584K - $584K
SIOUX FALLS, SD

High-grade serous ovarian carcinoma (HGSC) is the most common type of ovarian cancer and has the 3rd highest mortality-to-incidence ratio of all cance...

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NSFGEO-NERC: Carbon concentration and variability in Earth’s mantle

Due Feb 28, 2029
$537K - $537K
RAPID CITY, SD

What controls carbon concentration and variability in the Earth’s mantle is an important unanswered question. This project will address this question ...

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CAREER: Evaluating models of intracratonic structural reactivation: A case study of the Black Hills, western South Dakota

Due May 31, 2030
$520K - $520K
RAPID CITY, SD

Earth’s continents have grown progressively throughout geologic time by aggregation of crustal blocks along major fault zones. As a result, continenta...

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Probing the mechanisms of dependency underlying skeletal genetic pathways of p53 and Notch in the pathogenesis of osteosarcoma

Due Mar 31, 2030
$490K - $490K
SIOUX FALLS, SD

The goal of this proposal is to understand cancer dependency pathways that regulate premalignant osteoblasts and the development of osteosarcoma. Oste...

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Aptamers as Novel Inhibitors of the Neurotoxin Beta-methylamino-L-alanine (BMAA)

National Institute of Environmental Health Sciences·Due Jul 31, 2028
$484K - $484K
SPEARFISH, SD

Exposure to specific environmental factors are believed to play a role in the development of many neural pathologies. Early studies linked chronic exp...

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Neurotrophic Drug Development for Alzheimer's Disease

Due Mar 22, 2027
$475K - $475K
SIOUX FALLS, SD

Drug development for the cognitive deficits in Alzheimer’s Disease has proven to be challenging. Although major progress has been made in understandin...

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REU Site: Black Hills Applied Ceramic Engineering

Due Aug 31, 2027
$457K - $457K
RAPID CITY, SD

Ceramics are used in many industries and various applications that range from thermal insulators for spacecraft to more practical applications like br...

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Regulation of Nucleocytoplasmic Compartmentalization

Due Jan 31, 2031
$457K - $457K
SIOUX FALLS, SD

/ABSTRACT The nuclear envelope is a specialized extension of the endoplasmic reticulum that surrounds the eukaryotic cell nucleus, effectively compart...

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BRC-BIO: Mechanistic regulation of dynamic gene expression patterns by temporal JNK activation

Due Apr 30, 2028
$453K - $453K
BROOKINGS, SD

A fundamental feature of life is the ability to process information to initiate an appropriate response. This research project seeks to understand how...

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