Top Grant Opportunities

Preview the top 100 highest-funded grants from our database of 100,330+ opportunities. No account needed.

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Listings refreshed daily from Grants.gov, state portals, and curated foundation sources.

100,330
Open grants
0
Forecasted
51
States covered
25,844
scope:national

100 grants found

Page 1 of 5

FEMA Counter-Unmanned Aircraft Systems Grant Program for AI-Enabled Drone Detection

Federal Emergency Management Agency (FEMA) / Department of Homeland Security
$5.0M - $250.0M
TXFLNYNJCAGAMOKSMAWAPAcounter_dronehomeland_securityai_detectionpublic_safety

The FEMA Counter-Unmanned Aircraft Systems (C-UAS) Grant Program, established under the One Big Beautiful Bill Act of 2025, provides $500 million to e...

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DHS Counter-Unmanned Aircraft Systems (Counter-UAS) Grant Program FY2026 for AI-Enabled Drone Defense at FIFA World Cup and National Capital Region

U.S. Department of Homeland Security (DHS)
$1.0M - $30.0M
CAFLGAMAMONJNYPATXWADCcounter_uasai_drone_defensecomputer_visionsensor_fusion

The DHS Counter-Unmanned Aircraft Systems (Counter-UAS) Grant Program was established to support state and local law enforcement, critical infrastruct...

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Abandoned Mine Land Economic Revitalization (AMLER) Program

Pennsylvania Department of Environmental Protection (DEP), administered by the Office of Surface Mining Reclamation and Enforcement (OSMRE)
Up to $29.3M
Pennsylvaniaenvironmental_justicewater_qualityair_qualityland_conservation

Abandoned Mine Land Economic Revitalization (AMLER) Program is a grant from the Pennsylvania Department of Environmental Protection (DEP), administere...

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BioFoundry: Artificial Intelligence-Driven RNA BioFoundry

Due Aug 31, 2030
$11.9M - $11.9M
PHILADELPHIA, PA

The Artificial Intelligence-driven RNA BioFoundry (AIRFoundry) addresses critical challenges in RNA technology research by establishing a user-friendl...

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Category I: Bridges-3: Integrating AI, Data & HPC to Advance American Scientific Leadership

National Science Foundation·Due May 31, 2027
$10.0M - $10.0M
PITTSBURGH, PA

Bridges-3 is the continuation of PSC’s long standing role in providing production quality national cyberinfrastructure through the NSF Advanced Comput...

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THE NIH PRECISION BRAIN HEALTH NETWORK: Open and Inclusive Measurement of Neuropsychological Change for AD/ADRD Primary Prevention Trials

Due Jul 31, 2030
$7.9M - $7.9M
UNIVERSITY PARK, PA

Accurate and sensitive measurement of neuropsychological change is essential for advancing dementia prevention, especially during midlife when changes...

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ExpandQISE: Track 2: Research and Education Center for Quantum Materials and Sensing at a Women's College

Due Sep 30, 2029
$5.0M - $5.0M
BRYN MAWR, PA

The project aims to establish a Research and Education Center for Quantum Materials and Sensing at Bryn Mawr College, a Women’s College with a small c...

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National STEM Teacher Corps Pilot Program: Elevating Elementary Teachers as the Frontier of STEM Education

Due Sep 30, 2030
$5.0M - $5.0M
UNIVERSITY PARK, PA

The National STEM Teacher Corps Pilot Program Regional Alliance project "Elevating Elementary Teachers as the Frontier of STEM Education" aims to reco...

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Leveraging inter-individual differences in walking pain and impairment to elucidate whole-person mechanisms of knee osteoarthritis

National Institute of Arthritis and Musculoskeletal and Skin Diseases·Due Aug 31, 2029
$4.9M - $4.9M
PITTSBURGH, PA

/Abstract Knee osteoarthritis (OA) is a common and debilitating condition, affecting millions in the United States of America. From 1990 to 2020, OA r...

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Center: National Synthesis Center for Emergence in the Molecular and Cellular Sciences

Due Apr 30, 2029
$4.8M - $4.8M
UNIVERSITY PARK, PA

The National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) is a national resource driving innovation by enabling inter...

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Nonpoint Source Implementation Grant Program

EPA Region 3
Up to $4.8M
Pennsylvaniawater_qualityenvironmental_justicecommunity_developmentnonpoint source pollution

Nonpoint Source Implementation Grant Program is a grant from EPA Region 3 that funds state agency implementation of nonpoint source pollution manageme...

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Genomic and exposomic factors in the cause and rise of autism

Due Sep 28, 2028
$4.3M - $4.3M
PHILADELPHIA, PA

This collaboration between the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn) focuses exactly on the key priorit...

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Rationally designed targeted immunogens to elicit HIV Envelope V2-apex broadly neutralizing antibodies

Due May 31, 2030
$4.2M - $4.2M
PHILADELPHIA, PA

OVERALL: PROJECT SUMMARY Our primary goal in this IPCAVD program is to develop a germline-targeting priming immunogen for the HIV Envelope V2-apex bro...

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Institute for Computer-Aided Reasoning in Mathematics

Due Aug 31, 2028
$4.1M - $4.1M
PITTSBURGH, PA

The Institute for Computer-Aided Reasoning in Mathematics (ICARM) is a national institute dedicated to catalyzing fundamental advances in mathematics ...

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The Oro-Respiratory-Gut Virome Axis Over Space and Time

Due Jan 31, 2030
$4.0M - $4.0M
PHILADELPHIA, PA

The human virome is vast, differs among human individuals, and changes over the human lifespan. While the virome influences human health in many ways,...

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Administrative and Outreach Core

Due Aug 31, 2026
$4.0M - $4.0M
PHILADELPHIA, PA

The Administrative and Outreach Core of the Kids First Data Resource Center will drive the use of the KF DRC data and tools through dynamic innovative...

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Kids First Pediatric Data Resource Center

Due Aug 31, 2026
$4.0M - $4.0M
PHILADELPHIA, PA

Since its launch, the Gabriella Miller Kids First Data Resource Center (KFDRC) has constantly innovated and helped redefine the architecture, developm...

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Cross Scale Interrogation of NPD Genes (SING) in mice

Due Nov 30, 2029
$3.8M - $3.8M
HERSHEY, PA

Neurodevelopmental and psychiatric disorders (NPDs) are highly prevalent and devasting neurological conditions without cure. Recent genetic studies on...

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Mild Cognitive Impairment: A Prospective Community Study

Due Apr 30, 2031
$3.8M - $3.8M
PITTSBURGH, PA

Mild Cognitive Impairment: A Prospective Community Study. Dementia is a leading cause of disability and death in older adults. Its incidence increases...

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Improving Health Through HUD Housing Assistance for Chronic Disease Care

Due Aug 31, 2029
$3.7M - $3.7M
PHILADELPHIA, PA

Housing is closely linked to health outcomes, and stable housing is essential for overall health and wellbeing. Housing provides continuity in home en...

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